Flowers in Bangalore... |
7th
ISAP International Symposium
Advances in the Pharmacology of Antiinfective Therapy co-sponsored with Astra Research Centre, India (ARCI) January 20-22 (Thursday - Saturday), 2000 National Science Seminar
complex, Indian Institute of Science,
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One of the main goals of ISAP is to disseminate the concepts as well as the practical knowledge of Pharmacokinetics and Pharmacodynamics (PK/PD) of antiinfectives within the scientific and clinical community. In this context, ISAP is regularly sponsoring scientific meetings where ISAP members and/or experts in PK/PD of antiinfectives address invited audiences to review the recent progresses, discuss their potential applications and answer specific questions in their domains of expertise.
The present
meeting is typically meant at bringing to an international audience, with
emphasis on Asia, the knowledge developed by ISAP over the last years through
the scientific activities of its members on the one hand and through contacts
with regulatory agencies on the other hand, so that new drugs will be used
in the most appropriate fashion with respect to the three main criteria
of efficacy, lack of toxicity and prevention of emergence of resistance.
The symposium deals with pharmacodynamic and parmacokinetic properties
of antibacterial agents as determined in in vitro and in vivo
models and their use for prediction and evaluation of the performance of
the agents and the use of this information for development, clinical use
and registration of
the latter. Special attention
will also be given to tuberculosis, an old but still highly threatening
disease in emerging countries.
The meeting is open all scientists in academia and industry. The focus of the programme is on active interaction with the audience in order to provide both researchers and clinicians an as effective as possible guidance for successful future work and achievements in antiinfective therapy.
Organizers: Prof. O. Cars (ISAP & University Hospital, Uppsala, Sweden) & Dr. B. Ekstrom (Astra Research Centre India)
|
Thursday, January 20th |
||
| 3:00pm | Registration | |
| 4:00 pm | Inauguration | N.K. Ganguly
Indian Council of Medical Research, New Delhi, India |
| 4:30 - 5:30 pm | Plenary
lecture:
Trends & Problems in Therapy with Antibacterial Drugs (introduced by Dr B. Ekstrom, Astra Research Centre, India) |
Otto Cars,
University of Uppsala, Uppsala, Sweden |
| 5:30 pm | Refreshments and "Get together" | |
|
Friday, January 21st |
||
| Session
1: Pharmacokinetic & Pharmacodynamic Concepts
|
||
| 9:00 am | Pharmacokinetic concepts | Otto Cars,
University of Uppsala, Uppsala, Sweden |
| 9:45 am | Pharmacodynamic concepts | William A. Craig,
University of Madison, Madison, WI |
| 10:30 am | Coffee | |
| 11:00 pm | Intracellular pharmacodynamics | Paul M. Tulkens
Catholic University of Louvain, Brussels, Belgium |
| 11:45 | Session discussion | |
| 12:00 | Lunch | |
| Session
2: In Vitro and In Vivo Studies for Prediction
of Clinical Efficacy and Dosing
|
||
| 1:00 pm | In vitro pharmacodynamic models in the development of antibacterials | E. Löwdin,
University of Uppsala, Uppsala, Sweden |
| 1:45 pm | Animal models in early evaluation of antibacterial agents | N. Frimødt-Møller,
University of Copenhagen, Copenhagen, Denmark |
| 2:30 pm | Use of animal models to define pharmacokinetic and pharmacodynamic interactions and optimal doses of antibacterial drugs | William A. Craig, M.D.
University of Madison, Madison, WI |
| 3:15 pm | Session discussion | |
| 4:00 | Tea & Coffee | |
| Session 3:
Interacting with the audience -- PK/PD in action
|
||
| 4:00 - 6:00 pm | Slide Presentations and Panel Discussion on:
In vivo models for the determination of antibacterial efficacy: advantages and limitations |
Chair: N. Frimødt-Møller,
University of Copenhagen, Copenhagen, Denmark |
| 6:00 pm | Adjourn | |
| 8:00 pm | Dinner | |
|
Saturday January 22d |
||
| Session
4: Resurgence of Tuberculosis
|
||
| 9:00 am | Problems in the treatment of tuberculosis | J. Nachega
School of Public Health, Johns Hopkins University, Baltimore, MD |
| 9:30 am | Prediction of clinical efficacy of antitubercular regimens from in vitro studies | C. Paramasivan,
Tuberculosis Research Centre, Chennai, India |
| 10:15 am | Animal efficacy studies of antitubercular agents | V. Balasubramanian,
AstraZeneca R&D Indian Site, Bangalore, India |
| 10:45 am | Session discussion | |
| 11:00 am | Coffee and Poster viewing | |
| Session
5 : Clinical Studies
|
||
| 11:30 am | Design of Clinical Studies of Antibacterial Agents for Efficacy and Toxicity | R. Norrby,
Departement of Infectious Diseases, Lund University Hospital, Lund, Sweden |
| 12:15 pm | Evaluation of Clinical Efficacy and Optimal dosing from Clinical Trials. | G. L. Drusano,
Albany Medical college, Albany, NY |
| 1:00 pm | Lunch | |
| 2:00 pm | Prediction and prevention of emergence of resistance of clinically used antibacterials. | F. Baquero,
Ramon y Cajal Hospital, Madrid, Spain |
| 2:45 pm | Session discussion | |
| 3:00 pm | Coffee and Tea | |
| Session 6: Documentation
and development of new antibacterial agents
|
||
| 3:30 pm | Regulatory efficacy requirements of new antibacterial drugs | Speaker to be announced |
| 4:15 pm | Industrial Aspects of the development of Antibiotics | Jeff Edwards,
AstraZeneca R&D British Site, Alderley Park, UK |
| 5:00 pm | Closing Remarks:
|
|
| 5:30 pm | Close of the meeting | |
Registration is open to all ISAP members and to all professionals active or having interest in the pharmacokinetics and pharmacodynamics of antiinfective agents. No fee will be collected but Registration is essential for administrative purposes.
To register, use our On-line Registration form (preferred !), or the Printable Registration form
Registration entitles to full attendance to the scientific sessions, complimentary coffee and coffee/tea breaks, lunches and the Friday January 21st dinner. Registration does not include accomodation, other meals than those mentionned above, or travel expenses. Alle these must be borne by the registrant. Astra Research Centre will assist the registrants in making hotel reservations. The contact e-mail address for these matters is <mandyam.mukund@astrazeneca.com>.
IMPORTANT
REMARK: ATTENDANTS FROM OUTSIDE INDIA MUST HAVE A VALID
VISA TO ENTER INDIA. THIS VISA MUST BE APPLIED FOR AT THE CLOSEST
DIPLOMATIC MISSION OF INDIA IN THEIR COUNTRY OF CITIZENSHIP OR PERMANENT
RESIDENCE (CONSULAR OFFICES OR EMBASSY OF INDIA). BECAUSE OF
POSSIBLE DELAYS, ATTENDANTS ARE ADVISED TO MAKE THEIR APPLICATION WELL
IN ADVANCE OF THEIR EXPECTED DATE OF DEPARTURE.
National Science Seminar
complex,
Indian Institute of Science
(IISc),
Bangalore, Kartnaka,
560 012 India
telephone (main switchboard):
+ 91 - 80 - 334-4411 (7 lines)
fac-simile (mai office):
+ 91 - 80 - 334-1683 or 334-2085
cable (telegram): <science
bagalore 560 012>
E-mail (main office): regr@admin.iisc.ernet.in
maps, directions and transport informations (Location of Bangalore in India, Region of Bangalore, City of Bangalore, Campus of the Indian Institute of Science with the location of the Lecture Hall [National Science Seminar Complex], general information on transport in Bangalore).
Tip: for visitors arriving by cab, note that IISc is popularly known as "Tata Institute" In Bangalore city. At least many of the cab drivers won't understand otherwise.see also the Web site of the The Indian Institute of Science in Bangalore for detailed information on theis Institute.
No accomodations will be
provided by ISAP. See <Registration> for informations regarding
accomodation
ARCI is situated in Bangalore, state of Karnataka, India and was founded in 1986. It is a non-profit organization, a Society under the laws of Karnataka, with the objective to support scientific developments in India, particularly with regard to infectious diseases. The Society, comprising Indian and Swedish scientists as members, is headed by a Director, Dr. S. Anand Kumar and has a Governing Board with three members appointed by the Government of India, Department of Science and Technology and three members appointed by Astra AB, Sweden (now AstraZeneca, PLC, UK). The activities of ARCI are financed mainly by returns on a corpus fund owned by the Society and to some extent by a contribution from AstraZeneca. The Society has decided to change its name into AstraZeneca Research Foundation India but the new name has not yet become official.
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