One of the main goals of ISAP is to be a forum for presenting new concepts and new data pertaining to the pharmacokinetics and pharmacodynamics of antiinfective agents.  These new concepts and data which may, possibly, become part of the basic aspects of antiinfective chemotherapy.
 

Over the years, the symposium which ISAP has held just after of before the Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) has become specifically devoted to this type "New concept/New data" discussion meeting (see the sections "Past meetings and activities" and "Forthcoming meetings" for other post-ICAAC meetings as well as for other types of activities such as co-sponsored symposia and workshops).  This year's meeting was no exception to this rule and the programme has foced both on controversial issues, where new data and discussions are needed, as well as on the presentation of the  and pharmacokinetics pharmacodynamics of new agents.   Ample time was devoted to an in depth discussion among all participants based on presentations, each of them being informative, and even sometimes provocative, but concentrating always on new concepts and data at the cutting edge of the Science of pharmacokinetics and pharmacodynamics.   In parallel to the main session, posters were on display for the whole duration of the meeting.  A "Young Investigator" fellowship was awarded to J.M. Michot, Pharm. (Brussels, Belgium) for a poster on fluoroquinolone efflux from eucaryotic cells.

Computer modeling of drug-target interactions: how does it work ? (R. Brasseur, Gembloux, Belgium) Computer modeling of dosing optimization: where are we ? (J.J. Schentag, Buffalo, NY) Cell culture methodologies for assesment of  pharmacodynamics  (Paul M. Tulkens, Brussels, Belgium) In situ determination of antibiotic concentrations by microdialysis and prediction of clinical outcome (Christian Joukhadar, Vienna, Austria) Can we trust animal models to set up safe antibiotic breakpoints ? (William A. Craig, Madison, WI)  PK/PD methodologies to prevent  emergence of resistance in clinics  (J.J. Schentag, Buffalo, NY) PK/PD methodologies to prospectively assess the risk of emergence of resistance towards novel antibiotics (Michel N. Dudley, Mountain View, CA)

Back to ISAP home page 

• The ISAP Web site and ISAP diffusion list are kindly and generously housed on the INTERNET Server of the Faculty of Medicine of the 'Université Catholique de Louvain' in Brussels, Belgium, with the expert help of Benoît Debande, MD.  All comments and queries should however be sent exclusively to the ISAP Webmaster.
• Fishing in lake Ontario: Lake Ontario is famous for its fishes.  In August-October,  Coho and Chinook salmon many up to 30 pounds and some exceeding 40 pounds abound. Battle with one of these powerful heavyweights- freshwater fishing's greatest challenge...  These pictures are taken from the Web site of the Great Rochester Fisheries Association, Rochester, NY (almost opposite to Toronto, Ont.)
• The other pictures and logos are from the WEB sites to which they are linked