Magnitude of PK/PD Parameter Required for Effective Dose-50 Against Candida albicans in Kidneys of Neutropenic Mice

Drug MIC ED-50 AUC/MIC

Fluconazole 0.5 1.9 24

16 61 15

32 114 20

Andes & vanOgtrop, AAC 44:943, 2000

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