The general concept of Pharmacokinetics

12/06/2000

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Table of Contents

Pharmacokinetics

Volume of Distribution

Bioavailability Rate and Extent of Absorption

Intravenous bolus

Intravenous bolus

Intravenous bolus

The AUC within a dosing interval at steady state is equal to the total AUC of a single dose.

Intravenous bolus

First-order absorption

Oral administration

Oral administration

Oral administration

Zero-order absorption

Constant rate infusion

Constant rate infusion

Two-compartment model

Two-compartment model

Two-compartment model

Two-compartment model

Two-compartment model

Two-compartment model

Three-compartment model

Author: Hartmut Derendorf

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Home Page: http://www.isap.org/2000/Workshop-Stockholm/intro.htm