8th ISAP Symposium
Developments in Pharmacokinetics and Pharmacodynamics (PK/PD):
optimizing efficacy and prevention of resistance
Nijmegen, The Netherlands, July 4th-6th, 2001

Rational Dosing of Antimicrobial Drugs in Animals

Click here to start

Table of Contents

Rational Dosing of Antimicrobial Drugs in Animals

Pharmacology of Antimicrobial Therapy

Application of PK/PD integration to optimisation of antibacterial therapy

Antimicrobial Drug Treatment

Criteria for Setting Dose Schedules

Aspects of Pharmacokinetics in Animals

Elimination Half-life of Antimicrobial Agents : Species Differences

Oral Dosing of Antimicrobial Drugs in Ruminants

Parenteral Dosing of Antimicrobial Drugs in Ruminants and Pigs

Use of Depot/Sustained Release Formulations

Residues of Antimicrobial Drugs in Food Producing Species

Drug Pharmacokinetics in Mastitis Therapy in Cattle

Milk : Plasma Concentration Ratios in Cattle

Drug Pharmacokinetics in Mastitis Therapy in Cattle

Intramammary Dosing of Antimicrobial Drugs in Ruminants

PHARMACOKINETIC (and Efficacy ?) Variability of Antimicrobial Drugs in Poultry

Poultry Unique Anatomical Considerations

Poultry Unique Anatomical Considerations

Excretory / urinary systems

PHARMACOKINETIC (and Efficacy ?) Variability of Antimicrobial Drugs in Fish

Elimination Half-life of Antimicrobial Agents in Fish : Species and Temperature Differences

Antibacterial Therapy in Fish

Bacterial Disease in Bees

European Foulbrood

Tissue Cage Model of Acute Sterile Inflammation

PK/PD Integration of Fluoroquinolones Tissue Cage Model of Sterile Inflammation

AUC24h / MIC Values and Hill Constants for Danofloxacin Determined Ex Vivo in the Goat

Ex Vivo AUC24h/MIC Values for Danofloxacin in Serum from Ruminant Species

Preliminary Study of Danofloxacin AUC/MIC in Calf Model of Pneumonia

Proposal for Future Studies Clinical Disease e.g. Calf Pneumonia

Distribution of MIC

PK/PD Integration of Antimicrobial Drugs in Clinical Trials

Acknowledgments

Author: Fariborz Shojaee & Peter Lees

Email: webmaster@isap.org

Home Page: http://www.isap.org/slides.htm

Important note:

These slides are for information only. Do not make public use of them without autorization of the author and of the ISAP Webmaster

Download presentation source