A Mouse Model of Established Mixed Infection Abscesses

Table of Contents

Intra-abdominal (Mixed infection) Abscesses

Animal Models of Intra-abdominal Abscess 

Uses of Mixed Infection Subcutaneous Abscess Model

Subcutaneous Murine Abscess Model Adjuvant: Autoclaved Cecal contents (ACC)

Methods (1)

Methods (2)

Effect of different inocula on abscess development

Histology of Abscesses Day 1

Histology of Abscesses 

Effect of abscess development on the efficacy of Imipenem 384 mg/kg/d (q4) 3 days

Development of Abscesses first week 4 mg Autoclaved Cecal Contents (ACC)

Histology of Abscesses Day 8 Goldner stain

Pharmacokinetics in serum in abscess and in pus Imipenem single dose of 128 mg/kg

Efficacy of Ceftizoxime on bacterial counts

Effect of a Single Closed Drainage Puncture on abscess size and bacterial counts

Effect of Abscess Drainage on the Efficacy of Imipenem MIC E. coli 0.125 MIC B. fragilis 0.06

Pharmacokinetics of Trovafloxacin in Serum Single Dose of 150 mg/kg

Trovafloxacin Concentrations in Abscesses After a Single Dose of 150 mg/kg

Efficacy of Trovafloxacin: B. fragilis / E.coli Combination

Biodistribution of 99mTC-IgG After treatment with 5 days of Trovafloxacin

Subcutaneous Murine Established Abscess Model 

Subcutaneous Murine Established Abscess Model 

Subcutaneous Murine Established Abscess Model co-workers

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