Getting deep in PK/PD ...

getting deeper with PK/PD ...

11th ISAP International Symposium
PK/PD : younger (and deeper) views...
(a post-ICAAC 2002 meeting) 
 
 
date and time: 
September 30th (Monday) afternoon
Place: 
San Diego Marriott Hotel & Marina, Marina Ballroom E, 3rd floor, south tower.


Goals and objectives

    One of the main goals of ISAP is to be a forum for presenting new concepts and new data pertaining to the pharmacokinetics and pharmacodynamics of antiinfective agents.  These new concepts and data may, possibly, become part of the basic science of antiinfective chemotherapy.

   Over the years, the symposium, which ISAP helds just after the Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) has become specifically devoted to this type "New concept/New data" discussion meeting (see "Past meetings and activities").

    This year's meeting will be no exception to this rule and the programme will focus both on controversial issues, where new data and discussions are needed, as well as on the presentation of the  and pharmacokinetics pharmacodynamics of new agents.

    The focus of the programme this year is also in bringing new views, and to discuss new topics.  Effort will be made towards a real, in depth discussion among all participants based on presentations meant to be informative, and even sometimes provocative, but concentrating always on new concepts and data at the cutting edge of the Science of Pharmacokinetics and Pharmacodynamics of Antiinfectives.



Programme

Programme last update: September 14th, 2002

Organizer: George L. Drusano (Albany, NY) and Johan W. Mouton (Nijmegen, The Netherlands)
 
 
3:00 pm
Registration, Poster viewing, and sandwiches/soft drinks 
3:25 pm
ISAP Welcome and Introduction
Session #1 :  Younger (and deep) views ...
3:30 pm Pharmacokinetic/Pharmacodynamic (PK/PD) Evaluation of a Once-Daily Treatment Using Ciprofloxacin in a Modified-Release (MR) Dosage Form

Edgar Schuck
University of Florida,
Gainesville, FL

3:45 pm Proof of Concept Study Design for SPD 754 Based on Clinical Trial Simulation
Patrick Smith
Buffalo, NY
4:00 pm A novel mathematical model for interpreting kill-curve data
Brent Booker
Buffalo, NY
4:30 pm
A Novel PK/PD Model for Prediction of Outcomes with a Modified Release (MR) Formulation of Ciprofloxacin (CIP)
Alison Meagher
Buffalo, NY
4:45
Effect of ceftizoxime (CZX) and piperacillin/tazobactam (PT) dosing on efficacy and mutation frequency (MF) of Bacteroides fragilis (BF) and Enterobacter cloacae (EC) in mixed infection murine abscesses
Inge Gyssens
Rotterdam, NL
5:00
Coffee / Tea and Poster viewing
5:15 pm
Monte Carlo Simulations of piperacillin to obtain Target Attainment Rates of T>MIC in Patients with Haematological Malignancies.
Jackeline Bos
Nijmegen, NL
5:30 pm
PK/PD relationships of rifampicin and isoniazid in an aerosol infection model of tuberculosis in mice.
Ramesh Jamaram
AstraZeneca, India
Session #2: Deeper (and young) views ...
5:45 pm A general discussion on hotly debated topics during this years ICAAC.
Introductory slides on

  • Monte Carlo Simulation (GL Drusano, Albany, NY)
  • Synergy Testing (JW Mouton, Nijmegen, NL)

General Discussion:
7:00 pm
Buffet Dinner and General Assembly



Poster Session

    Like for most other ISAP symposia devoted to the analysis and discussion of new concepts and data, each attendants is strongly encouraged to bring one poster describing his/her activities or recent data in relation to PK/PD of antiinfective agents (this poster may be the same or a slightly modified version from one presented at the 41st ICAAC).  Posters will be on display for the whole duration of the meeting and can be viewed during the regisitration time, at all intermissions, during the Buffet dinner, and at the close of the meeting.  Persons wishing to present a poster must tell the organizers in advance (preferably at the time of registration) to enable them to order the appropriate number of boards (approx. 2 m large x 1 m high).



Fellowships for young investigators

    ISAP wishes to encourage young investigators to attend its scientific meetings.  In this context, ISAP offers two (2) fellowships (US $ 500.- each) to young investigators who otherwise would be unable to attend the present meeting (this fellowship may complement other sources raised to attend ICCAC is these do not provide the necesssary amount for the additional day in Toronto, Ont., or are clearly unsufficient).

    Please, contact the Secretary (Johan W. Mouton, MD PhD, Department of Medical Microbiology, Canisius Wilhelmina Hospital, Weg door Jonkerbos 100, NL-6532 SZ Nijmegen, The Netherlands;  E-mail: <secretary@isap.org>; tel: +31-24-365 7514;  fax: +31-24-365 7516) before September 5th, 2002.  Submit a formal request supported by the necessary documentation of interest (abstract of poster) and provide evidence that you cannot raise money for attending out of your regular sources of funding or from money raised to attend ICAAC.  Fellowships will be awarded based on scientific merits and of perception of a financial need.

    Notification to succesful applicants will be made by September 15, 2002.   Actual payment of the fellowships will be made at the time of the meeting



Registration

Registration is open to all ISAP members and to all professionals active or having ineterest in the pharmacokinetics and pharmacodynamics of antiinfective agents.All attendants (including ISAP members) must register to enable the organizers to make the appropriate food and beverage orders.

Registration fees:

To register, use  the On-line Registration form (you can also print this form and fax it if you prefer)

Venue

San Diego Marriott Hotel & Marina, Marina Ballroom E, 3rd floor, South Tower.



Accommodations

No accomodations will be provided by ISAP.
Persons attending the 42d ICAAC may make use of their hotel resrevation facilities.  Otherwise, see useful links below.


Useful links
 
San Diego at night ...
42d ICAAC Contemporary Arts ...
Cooking ...

Last update:August 14th, 2002

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Credits:
last significant update: June 18th, 2000