The General Concepts of Pharmacokinetics and Pharmacodynamics

H. Derendorf  (Department of Pharmaceutics, University of Florida, Gainsville, FL) 

7th ISAP Pharmacokinetics / Pharmacodynamics (PK / PD) Educational Workshop
San Diego, CA. September 26th, 2001

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Table of Contents

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Pharmacokinetics

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Clearance

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Volume of Distribution

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Half-Life

Protein Binding

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Microdialysis

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Bioavailability Rate and Extent of Absorption

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Intravenous bolus

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Intravenous bolus

Intravenous bolus

First-order absorption

Oral administration

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Oral administration

Oral administration

Zero-order absorption

Constant rate infusion

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Constant rate infusion

Two-compartment model

Two-compartment model

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Two-compartment model

Two-compartment model

Short-term infusion

Three-compartment model

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Author: Hartmut Derendorf

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