The General Concepts of Pharmacokinetics and Pharmacodynamics

ISAP workshop, Glasgow UK, May 10th 2003

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Table of Contents

The General Concepts of Pharmacokinetics and Pharmacodynamics

Pharmacokinetics

Volume of Distribution

BioavailabilityRate and Extent of Absorption

Protein Binding

Pharmacokinetic profile of cefpodoxime (400 mg oral dose, n = 6)

Pharmacokinetic profile of cefixime (400 mg oral dose, n = 6)

Pharmacokinetics

Two-compartment model

Two-compartment model

Short-term infusion

Three-compartment model

Intravenous bolus

Intravenous bolus

Intravenous bolus

First-order absorption

Oral administration

Oral administration

Oral administration

Zero-order absorption

Constant rate infusion

Constant rate infusion

Two-compartment model

Two-compartment model

Author: Hartmut Derendorf

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