Protein binding and tissue concentrations – do they matter ?

8th ISAP Educational Workshop, Glasgow, UK, May 10th, 2003

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Table of Contents

Protein binding and tissue concentrations – do they matter ?

Tissue penetration - protein binding

Where is the pathogen?

Site of Infection

Where is the antibiotic?

Site of Infection

PPT Slide

Protein binding

Protein binding

Protein binding

Protein binding: Effect on Penetration of ß-Lactams into Rabbit Peripheral Lymph

Protein binding

Protein binding

Protein binding: Moxifloxacin

Protein binding: Ertapenem

Protein binding

Protein binding

Protein binding

What do we know about protein binding?

Tissue concentrations

Tissue concentration: pulmonary

Tissue concentration: pulmonary

Tissue concentration: pulmonary

Tissue concentration: middle ear

Tissue concentration: middle ear

Tissue concentrations: resistance

Tissue concentration – does it matter?

PPT Slide

Author: U. Theuretzbacher

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