13th ISAP International Symposium New regards to PK/PD ... (a post-ICAAC 2004 meeting)    date and time:  Tuesday November 2d, 2004, 1:30 pm - 7.00 pm (Lunch Buffet Dinner at 1:00 pm) Place: Renaissance Hotel (Meeting room 5)    999 Ninth Street NW    Washington, DC Goals and Objectives    Updated Programme !! Venue | Registration | Useful links | Credits

    One of the main goals of ISAP is to be a forum for presenting new concepts and new data pertaining to the pharmacokinetics and pharmacodynamics of antiinfective agents.  These new concepts and data may, possibly, become part of the basic science of antiinfective chemotherapy.

   Over the years, the symposium, which ISAP helds just after the Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) has become specifically devoted to this type "New concept/New data" discussion meeting (see "Past meetings and activities").

    This year's meeting will be no exception to this rule and the programme will focus both on controversial issues, where new data and discussions are needed, as well as on the presentation of the  and pharmacokinetics pharmacodynamics of new agents.

    The focus of the programme this year is also in bringing new views, and to discuss new topics.  Effort will be made towards a real, in depth discussion among all participants based on presentations meant to be informative, and even sometimes provocative, but concentrating always on new concepts and data at the cutting edge of the Science of Pharmacokinetics and Pharmacodynamics of Antiinfectives.

   Programme last update: October 21,  2004

Tuesday November 2d, 2004

Organizer: Johan W. Mouton (Nijmegen, The Netherlands)  

1:00 pm	Registration and Lunch Buffet
1:30 pm	ISAP business meeting / General Assembly
2:30 pm	A Novel Pharmacodynamic Model of Gatifloxacin (GAT) against Salmonella typhi in an in vitro Infection Model O.O. Okusanya, A. Forrest, B.M. Booker, J.M. Bullock, P.G. Ambrose, S.M. Bhavnani, P.F. Smith
2:50 pm	A Scoring Method Applicable to the Time-related Clinical and Microbiological Responses of Patients with Staphylococcus aureus LTRI J.J. Schentag, P.M. Moise-Broder, M.H. Adelman, A. Forrest,
3:10 pm	In vitro Pharmacodynamics of a Fluoroquinolone Against Anaerobes K.E. Bowker, A.R. Noel, A.P. MacGowan
3:30 pm	Pharmacodynamics and Pharmacokinetics of Colistin and Colistin Methanesulfonate J. Li, R.L. Nation, R.W. Milne, J.D. Turnidge, K. Coulthard, C.R. Rayner
3:50 pm	Ex-Vivo Human Placental Transfer of Indinavir S. Sudhakaran, H. Ghabrial, R.L. Nation, D.C.M. Kong, N.M. Gude, P.W. Angus, C.R. Rayner
4:05 pm	Inhibition of P-glycoprotein : Impact on Placental Transfer of Indinavir S. Sudhakaran, C.R. Rayner H. Ghabrial, D.C.M. Kong, N.M. Gude, P.W. Angus, R.L. Nation
4:20 pm	Coffee / Tea and Poster viewing
4:40 pm	Optimal Multi-drug PK Sampling Strategies for Efavirenz and Indinavir Q. Ma, A. Forrest, S. Rosenkranz, M.F. Para, E. Adams, K. Yarasheski, R.C. Reichman, G.D. Morse,  and the AACTG A5043 Protocol Team
5:00 pm	Optimal Sparse Pharmacokinetic Sampling Strategies for Multi-Drug Antiretroviral Regimens J. Zack, A. Forrest, Q. Ma, S. Rosenkranz, M.F. Para, E. Adams, K. Yarasheski, R.C. Reichman, G.D. Morse, and the AACTG A5043 Protocol Team
5:20 pm	A Population Analysis Showing that Cystatin C is an as Good Predictor as Creatinin Clearance for Cefuroxime Clearance. A. Viberg, M. Sandström, O. Cars, M. Karlsson.
5:40 pm	Pharmacokinetic and Pharmacodynamic Evaluation of Ciprofloxacin in Modeled Microgravity E.L. Schuck, M. Grant, L. Putcha, H. Derendorf
6:00 pm	Pharmacodynamics of Cefprozil Against H. influenza in Plasma and Middle Ear Fluid by Population Pharmacokinetic Modeling and Monte Carlo Simulation in Otitis Media P.F. Smith, A. Forrest, B.M. Booker, S.M. Bhavnani, P.G. Ambrose
6:20 pm	Humanization and Adaptive Study Design- 2 Novel Approaches to Improving The Efficiency and Precision of PK/PD Studies in Small Animals O.O. Okunsanya, A. Forrest, B.M. Booker, S.M. Bhavnani, D. Girard, P.G. Ambrose.
Closing Remarks and General Discussion

• Free for ISAP members (having paid their annual dues),
  
• 100 US$ for non members (including free ISAP membership for one year).
  
• Students: 25 US$

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