Note: The slides presented by the some of the speakers at this workshop are available on this site as "Web slide shows" and as ".PDF files". To view and/or to download them, click on the title of the lectures. These slides, which reflect the views of their authors and should not be taken as being endorsed by ISAP, are for information purposes only. They cannot be reproduced or used for any form of presentations without the autorization of their author and of ISAP. Please, contact the ISAP Webmaster for further information.

Pharmacokinetics and Pharmacodynamics (PK/PD) have now become essential tools for determining the appropriate use of currently available anti-infective agents as well as for accelerating the development of new drugs.  While this is now more and more recognized by Academia, Industry and Regulatory Agencies (see the ISAP / FDA and ISAP / EMEA workshops held in 1999, there is presently a lack of training into these disciplines.  Accordingly, ISAP has endeavoured to launch educational activities in this context.  The aim is to train people professionally involved in development or in the use of antiinfective drugs in the basic and applied aspects of pharmacokinetics and pharmacodynamics, showing how these sciences have emerged over the last 10 years and how their influence has grown.  This 12th workshop of ISAP will continue the tradition of European Educational Workshops initiated in 1999 at the occasion of the 9th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) (Berlin, Germany; see http://www.isap.org/Berlin-1999.htm).  This type of worshop has thereafter been organized at every subsequent ECCMID meeting (Stockholm, Sweden, 2000; Istanbul, Turkey, 2001; Milan, Italy, 2002; Glasgow, Scotland, 2003; and Prague, Czech Republic, 2004). 

• Objectives: Participants will gain insight in pharmacokinetic and pharmacodynamic concepts of antimicrobial therapy. This includes the use and application of  animal models and in vitro pharmacokinetic models. Attention will be given to pharmacokinetic issues (protein binding, the value of tissue concentrations), pharmacodynamic issues (the use of pharmacodynamic parameters to describe and predict effect, Sub-MIC effects, post-antibiotic effects, differences between in vitro and in vivo) and the use of pharmacokinetic/pharmacodynamic modelling (the E-max model and other models). To illustrate theory, examples will be given how to use the above concepts in clinical practice and drug discovery.
• Intended audience: physicians, clinical microbiologists, pharmacologists, pharmacists and anybody else interested.
• Level: basic to intermediate

Each participant will receive

• copies of all slides of all presentations (hand-outs) at the meeting and a link to a Web site for download of a full PDF version of all lectures (available about 10 days after the meeting) ;
  
• a certificate for participation.

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5. Useful links

	Home page of ISAP
	15th European Congress of Clinical Microbiology and Infectious Diseases [ECCMID]

• ISAP Web site and ISAP on-line services generously housed and managed on the INTERNET Server of the Faculty of Medicine of the 'Université Catholique de Louvain', Brussels, Belgium, with the expert help of Benoît Debande, MD.  All comments and queries should, however, be sent exclusively to the ISAP Webmaster.
• Spatial Triptich from the well known Danish artist Robert Jacobsen (Copenhagen, Denmark; 1912-1993) and member of the "CoBrA" (Copenhagen/Brussels/Amsterdam) group in the early 60's.  Robert Jacobsen sculptures are on display at The Carl-Henning Pedersen and Else Alfelt Museum in Herning, Denmark (located in mainland Denmark, about 40 km West of Aarhus).  Inaugurated in 1976, this is a well known "artist’s museums" in Denmark.
  
• other logos and pictures are from the WEB sites to which they are linked or are in the public domain.