14th ISAP Symposium
New developments in PK/PD: Evaluation of Anti-infective Activity and Resistance
A post-ECCMID meeting 
Copenhagen, Denmark, April 5th (16:00-19:00) - 6th (9:00-12:00), 2005

Kindgdom of Denmark
Scientific organizers: Niels Frimodt-Moeller (Statens Serum Institut, Copehagen, Denmark) and Jenny Dahl-Knudsen (Dept. of Clinical  Microbiology, H:S Hvidovre Hospital, Copenhagen, Denmark)



Goals and Format

    One of the main goals of ISAP is to be a forum for presenting new concepts and new data pertaining to the pharmacokinetics and pharmacodynamics of antiinfective agents.  These new concepts and data may, possibly, become part of the basic science of antiinfective chemotherapy.

   Over the years, the symposium, which ISAP helds just after the Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) has become specifically devoted to this type "New concept/New data" discussion meeting (see "Past meetings and activities").  The present meeting extend this concept to meetings held after the European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), which is becoming over the years the premier European Meeting devoted to Anti-infective Chemotherapy.   

    This year's meeting will be no exception to this rule and the programme will focus both on controversial issues, where new data and discussions are needed, as well as reviews on major issues important for the evaluation of the importance of pharmacokinetics and pharmacodynamics for effect in vivo of new agents.
   
    The focus of the programme this year is also in bringing new views, and to discuss new topics.  Effort will be made towards a real, in depth discussion among all participants based on presentations meant to be informative, and even sometimes provocative, but concentrating always on new concepts and data at the cutting edge of the Science of Pharmacokinetics and Pharmacodynamics of Antiinfectives.   



Programme

(some modifications to the programme and the schedule may be necessary; please check this page regularly for changes)

Tuesday April 5th
15:00
Registration

 16:00 Development of new drugs and how to predict in vivo efficacy from structure/in vitro-results.
A. Dalhoff,
University of Kiel, Kiel, Germany
16:45
Review the need for and use of animal models.
T. O'Reilly,
Novartis Pharma, Inc., Basel, Switzerland.
17:30
The importance of protein binding, and how to expose the highly protein-bound antimicrobials in the in-vitro models.
H. Derendorf
University of Florida, Gainesville, Fla.

18:15
Antifungal PK/PD: Clinical predictions from experimental models.
D. Andes
University of Wisconsin, Madison, WI
19:00
Ajourn
Depart for dinner


Wednesday April 6th
9:00
Future use of animal models in light of the restraints in their use, e.g. mortality as end-point. N. Frimodt-Moeller
Statens Serum Institute, Copenhagen, Denmark
9:45
How to model the MIC distribution ? J. Mouton
Canisius Whilhelmina Hospital, Nijmegen, The Netherlands
10:30
Therapeutic Drug Monitoring: pros and cons
F. Scaglione
University of Milan, Milan, Italy.
 11:15 Concerted research efforts in ISAP: Needs, fun, or out of the question ?
J. Dahl-Knudsen
  H:S Hvidovre Hospital, Copenhagen, Denmark
12:00
Closing Remarks
N. Frimodt-Moeller
Statens Serum Institute, Copenhagen, Denmark
J. Dahl-Knudsen
H:S Hvidovre Hospital, Copenhagen, Denmark
12:15 End of the meeting
Lunch




 Venue

The symposium will take place at the Statens Serum Institut, Copengahen.

Room and address: Auditorium (Foredragssalen), Building 43, 1st floor, Copenhagen S (see map). 

The Serum Institut is situated on the same island (Amager) as the The Copenhagen Bella Center [!! this link opens a new window], which is the conference center where ECCMID takes place). From the Bella Centre, take the metro to "Islands Brygge" (3 stops from the Bella Centre), and walk about 100 meters to the institute. 

Maps to the Statens Serum Institute: click on http://www.krak.dk, enter "
Artillerivej 5" on the field "Vej/husnr.:", click on  "Søg" (not "Slet" !!),  move down a little bit on the new window, find "Statens Serum Institut, Artillerivej 5, 2300 København S", and click on  "Kort" ....  you will get a nice map which you need to zoom out a little bit to get directions from the "Islands Brygge" metro station to the Institute (you will have also learned a few words of Danish...). 



Accomodation

ISAP will not be responsible for accomodation which must be taken care of individually by each participant.  Attendants participating to the 15th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) may wish to take advantage of their offerings (see Useful Links).



Registration

Registration is open to all professionals active or having interest in the pharmacokinetics and pharmacodynamics of antiinfective agents.

Please, register with the organizer (Prof. N. Frimodt-Moeller: E-mail: NFM@ssi.dk )

There is, so far, no registration fee but participants are expected to may for meals. 


5. Useful links

ISAP Home page of ISAP Staten Serum Institut
Statens Serum Institut, Copenhagen
 15th ECCMID
15th European Congress of Clinical Microbiology and Infectious Diseases [ECCMID]





Last update: November 11th, 2004

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