In Vitro Models of Infection for Preclinical Pharmacodynamic Modeling

25/03/99


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Table of Contents

In Vitro Models of Infection for Preclinical Pharmacodynamic Modeling

Pharmacokinetics/Pharmacodynamics as a Tool in Evaluating Antibiotic Efficacy

First Principles: Why Antibiotics Work In Vivo

Important Relationships Between Drug Exposure (Pharmacokinetics) and the MIC

What Can We Learn From In Vitro and Animal Models of Infection to Design Better Clinical Trials?

Differential Surface Analysis as Implemented in MacSynergy (Prichard and Shipman)

“Selected Spectrum Agents” for Resistant Organisms: The Special Case of Combination Therapy Antibiotic “Potentiators”

Animal and In Vitro Models of Infection for PK/PD Studies

One-Compartment In Vitro Pharmacodynamic Model of Infection

PPT Slide

In Vitro Pharmacodynamic Model

In Vitro Models of Infection

Summary: In Vitro and Animal Pharmacokinetic/Pharmacodynamic Models of Infection to Forecast Optimal Regimens for Humans

Author: Mike Dudley

Home Page: http://www.isap.org/past_activities.htm#ISAP/FDA workshop