PPT Slide
Why may anti-infectives be toxic?
From pharmacokinetics to toxicodynamics ...
Which Pharmacokinetic/Pharmacotoxicologic parameters to take in consideration ?
How can models help?
1. Toxicodynamic models for:
Toxicodynamic models for the understanding of aminoglycoside nephrotoxicity
2. Toxicodynamic models for:
Toxicodynamic models for the discovery of cellular alterations induced by macrolides
Pharmacokinetic parameters revisited in the light of toxicodynamics
Pharmacodynamic parameters revisited in the light of pharmacokinetics
Thanks to...
Email: webmaster@isap.org
Home Page: http://www.isap.org/Birmingham-1999.htm