PATTERNS OF KILLING OF BACTERIA

09/09/99

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Table of Contents

PATTERNS OF KILLING OF BACTERIA

Patterns of killing of bacteria

MIC - The root of all evil!

PPT Slide

Benefits of cidal activity

Time-kill curves I

Time-kill curves II

Emax model of bacterial kill 

Determinants of Emax

Determinants of Emax

Determinants of Emax

Antibiotics and Endotoxin

Competition of ß-lactam Antibiotics for the PBPs of Escherichia coli

PPT Slide

PPT Slide

Consequences of filamentation

Binding affinity (ID50) of some cephalosporins for HMW-PBPs of E.coli

PPT Slide

Pharmacodynamics of E.coli and cephalosporins

PPT Slide

Conclusions

Author: Ian Gould (with the help of Jacqueline Cooper)

Email: webmaster@isap.org

Home Page: http://www.isap.org/isap_icc_meeting-1999.htm