Annual meeting 2022
Optimised dosing of antibiotics – understanding PK/PD, clinical breakpoints and therapeutic drug monitoring
A 2 day course on PK/PD of anti-infectives was held as a pre-meeting to ECCMID at April 20 -21 2022 in Lisbon, Portugal. The course was organized in collaboration with EPASG and very well attended.
The program of the course can be found here.
ISAP General and Scientific Meeting
Immediately following the educational course, we held our general meeting and reflected on our scientific and educational acitivities of the past two years, followed by the traditional ISAP Young investigator session, chaired by Dr. Alina Nussbaumer-Pröll (Vienna) and Dr. Vincent Aranzana-Climent (Poitiers).
The slides of the general meeting can be found below. Access is restricted to ISAP members (please login to view attachment).
The following Young Investigators presented their work:
First name |
Last Name |
Title |
Aneeq |
Farooq |
Interaction screening of ceftazidime-avibactam and tigecycline against six clinical and nine isogenic E. coli and K. pneumoniae strains expressing carbapenemases |
Wisse |
Van Os |
Impact of individual ascitic fluids on bacterial growth and ceftriaxone effect in an in vitro model of spontaneous bacterial peritonitis |
Nicole |
Zimmermann |
Integrated in vitro approach to understand the exposure-effect relationship of fosfomycin against Escherichia coli |
Amaury |
O'Jeanson |
A model-based analysis of pharmacokinetic-pharmacodynamic (PK/PD) indices of avibactam against β-lactamase-producing Gram-negative bacteria |
Jinxin |
Zhao |
PhageGE: An Interactive Web-based R Shiny Application for Bacteriophage Pharmacology |
Sue |
Nang |
Elucidating the pharmacokinetics/ pharmacodynamics of bacteriophage therapy against Pseudomonas aeruginosa using a mouse bacteraemia model |
Romain |
Aubry |
Semi-mechanistic PKPD modelling of ceftazidime/avibactam and colistin combination against five multidrug resistant Klebsiella pneumoniae isolates |
Mathilde |
Lacroix |
In vitro PK/PD modelling of polymyxin B against resistant strain of A. baumannii in presence of mucin |
Matthias |
Gijsen |
Model-based TDM of vancomycin: a retrospective comparison with routine TDM-based dosing |
Gert-Jan |
Wijnant |
Pharmacokinetics and PK/PD of temocillin in non-ICU urinary tract infection patients with various stages of renal insufficiency |
Tim |
Ewoldt |
Large variability of unbound active fraction of ceftriaxone in contrast to ciprofloxacin in plasma of critically ill patients |
Maria |
Sanz Codina |
Relationship between pharmacokinetic/pharmacodynamic target attainment and microbiological outcome in critically ill COVID-19 patients with documented Gram-negative superinfections treated with meropenem continuous infusion |
ISAP Young Investigators
The audience voted for the best Young Investigator presentations:
Wisse Van Os (Medical University of Vienna, Austria)
Gert-Jan Wijnant (UCLouvain, Belgium)
The winner of the Young Investigator session Wisse van Os (3rd from left) and runner-up Gert-Jan Wijnant (3rd from right) together with the Young Investigator session chairs Alina Nussbaumer-Pröll and Vincent Aranzana Climent (right) and Sebastian Wicha (President of ISAP) and Markus Zeitlinger (Chair of EPASG) (left).
All attendees of the ISAP meeting.
Please login to get access to the slide deck (appears here after login)